Award
National Institute of Neurological Disorders and Stroke 1R21NS142731-01A1
Treatment of Neonatal Hypoxic Ischemic Injury with Echogenic Noble Gas Microbubbles
Recipient
NEW JERSEY INSTITUTE OF TECHNOLOGY
Award Amount
$426,456.00
Ceiling
$426,456.00
Awarded
May 07, 2026
Identifier
1R21NS142731-01A1
NIH/NINDS awarded approximately $426,456 to develop an innovative ultrasound-guided microbubble platform for delivering therapeutic noble gases to treat neonatal hypoxic-ischemic brain injury.
Description
This NIH-funded project aims to develop a novel ultrasound-guided microbubble platform for targeted delivery of therapeutic gases to treat neonatal hypoxic-ischemic brain injury, focusing on safety, efficacy, and long-term neurological preservation. The project involves testing noble gases xenon and argon encapsulated in microbubbles for treatment, developing a non-invasive, image-guided delivery platform using ultrasound, and researching neuroprotection and drug delivery systems.