Award
National Institute of Mental Health 5R01MH139201-02
The immunobiological mechanisms of depression in perimenopause
Recipient
Van Andel Research Institute, Grand Rapids, MI, United States
Award Amount
$765,613.00
Ceiling
$765,613.00
Awarded
January 16, 2026
Identifier
5R01MH139201-02
NIH funded research project to study immunobiological mechanisms of depression in perimenopausal women, aiming to develop biomarkers and therapeutic targets.
Description
This project aims to identify immunobiological mechanisms underlying the development of depressive symptoms in perimenopause. It seeks to develop biomarkers and therapeutic targets by studying plasma tryptophan metabolites, cytokines, epigenetic mechanisms in lymphocytes, and immune responses in women experiencing perimenopausal depression.