Award
National Institute of General Medical Sciences 2R35GM142553-06
Probing structural and biophysical mechanisms of mitochondrial membrane ultrastructure
Recipient
Massachusetts General Hospital, Boston, MA, United States
Award Amount
$477,018.00
Ceiling
$477,018.00
Awarded
May 07, 2026
Identifier
2R35GM142553-06
Research project funded by the National Institute of General Medical Sciences to study mitochondrial membrane ultrastructure and dynamics, aiming to understand membrane remodeling, response to stress, and evolutionary principles with implications for various diseases.
Description
The project investigates the molecular mechanisms that determine mitochondrial membrane shape, focusing on how mitochondrial membranes are remodeled at micron and nanometer scales, how morphology responds to environmental stressors, and principles of mitochondrial evolution. The research aims to contribute fundamental insights into structural cell biology and has implications for neurodegenerative diseases, cancer, and aging.