Award
NIH Reporter #2R37NS039600-25
Generation and Description of Neuronal Morphology and Connectivity
Recipient
George Mason University, Fairfax, VA, United States
Award Amount
$397,750.00
Ceiling
$397,750.00
Awarded
August 14, 2026
Identifier
2R37NS039600-25
The award funds research to generate and describe neuronal morphology and connectivity, developing computational models to study brain function and neurological disorders, with a focus on the hippocampal formation and memory-related impairments.
Description
This project aims to synthesize, analyze, and share quantitative information on neural morphology and the architectural organization of a mammalian brain region responsible for spatial representation and autobiographic memories. It involves creating detailed, data-driven, biologically plausible, full-scale, computationally predictive neural network models to investigate circuit dynamics of learning and related impairments. The research focuses on neural morphology and connectivity relevant to neuropathologies such as epilepsy and Alzheimer's, using computational approaches to study hippocampal formation function and impairments in episodic memory.