Award

National Cancer Institute 11404787

Targeting FOXA2/AP-1 axis to overcome lineage plasticity and therapy resistance in castration-resistant prostate cancer

Recipient

University of Massachusetts Boston (implied by the principal investigator's affiliation)

Award Amount

$418,610.00

Ceiling

$418,610.00

Awarded

January 09, 2026

Identifier

11404787

A research award by the National Cancer Institute to study and develop therapies targeting the FOXA2/AP-1 axis in castration-resistant prostate cancer, with a total funding of $418,610 over five years.

Description

Research project funded by the National Cancer Institute focusing on prostate cancer. The project aims to elucidate mechanisms of cellular identity shifts and develop combination therapies targeting the FOXA2/AP-1 axis to overcome lineage plasticity and therapy resistance in castration-resistant prostate cancer. The project duration is from February 21, 2025, to January 31, 2030.

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