Award
National Institute of Diabetes and Digestive and Kidney Diseases 5R01DK141142-02
Mechanisms of mitochondria-driven hepatocyte injury
Recipient
Utah State Higher Education System--University of Utah
Award Amount
$742,945.00
Ceiling
$742,945.00
Awarded
July 06, 2026
Identifier
5R01DK141142-02
NIH grant awarded to Utah State Higher Education System--University of Utah to study the role of EFHD1 in mitochondrial fission and liver injury, with a focus on potential therapeutic targets for metabolic liver diseases.
Description
This project aims to identify a critical transducer of hepatocyte mitochondrial fission, investigate whether inhibiting it can be protective in animal models of liver disease, and explore the mechanistic role of EFHD1 in mitochondrial remodeling and liver injury.