Award
National Heart, Lung, and Blood Institute 5R21HL175177-02
Role of specialized pro-resolving mediators of inflammation resolution in emphysema: analyses of SPIROMICS and LEEP
Recipient
ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI
Award Amount
$123,730.00
Ceiling
$123,730.00
Awarded
August 07, 2025
Identifier
5R21HL175177-02
NIH grant awarded to ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI to study the role of specialized pro-resolving mediators in emphysema using SPIROMICS and LEEP cohorts, with a focus on inflammation resolution and respiratory outcomes.
Description
This NIH-funded project investigates the role of specialized pro-resolving mediators in emphysema, aiming to identify disparities and associations with health outcomes to inform therapeutic strategies. The study will leverage data from the SPIROMICS cohort and validate findings in the LEEP cohort to determine if greater plasma circulating SPM concentrations are associated with improved respiratory outcomes in individuals with emphysema.