Award
NIH Reporter #1R21AI190343-01
PRG4/Lubricin glycoform variants associated with endocardial infections and sepsis
Recipient
National Institute of Allergy and Infectious Diseases (NIAID)
Award Amount
$448,375.00
Ceiling
$448,375.00
Awarded
September 16, 2025
Identifier
1R21AI190343-01
NIH awarded a grant to develop rapid detection methods for PRG4 glycoforms in plasma to study their role in sepsis, involving advanced glycoproteomics and ELISA techniques.
Description
This project aims to develop methods for rapid detection of PRG4 glycoforms in plasma and assess their prevalence in sepsis patients. It involves glycoproteomics mass spectrometry and ELISA development. The project is funded by NIH and involves collaboration with research institutes in California.