Award
National Institute on Aging 5R01AG076433-04
Deciphering hormonal regulation of neutrophil biology
Recipient
University of Southern California, Los Angeles, CA, United States
Award Amount
$504,392.00
Ceiling
$504,392.00
Awarded
July 01, 2025
Identifier
5R01AG076433-04
The award supports research on the impact of sex hormones and chromosomes on neutrophil biology and immune responses, using innovative models to understand sex-dimorphic immune regulation throughout life.
Description
This project investigates how sex hormones and sex chromosomes regulate neutrophil immune functions throughout life, using an adult somatic-sex reprogramming model to distinguish hormonal versus genetic effects. It aims to provide insights into sex-dimorphic immune regulation and lifelong hormonal impacts.