Award
National Cancer Institute 5R01CA231396-05
TRPV1 nociceptors in oral carcinogenesis and pain
Recipient
NEW YORK UNIVERSITY
Award Amount
$615,159.00
Ceiling
$615,159.00
Awarded
June 06, 2025
Identifier
5R01CA231396-05
A multi-year NIH grant awarded to study TRPV1+ nociceptors' role in oral cancer and pain, aiming to develop targeted therapies and reduce opioid use.
Description
The project focuses on understanding the role of TRPV1+ nociceptors in oral cancer and pain. The research aims to elucidate innervation types, measure neuron sensitization, and evaluate cancer promotion via TRPV1+ neurons. The project involves clinical and animal model studies. The project is significant for developing targeted therapies to manage oral cancer pain and potentially reduce opioid use.