Award
National Cancer Institute 4R01CA279487-04
Development of a precision medicine platform for circadian based therapeutics in pancreatic cancer
Recipient
University of Texas Health Science Center Houston
Award Amount
$1,461,750.00
Ceiling
$1,461,750.00
Awarded
September 18, 2025
Identifier
4R01CA279487-04
Award for developing a precision medicine platform targeting circadian-based therapeutics in pancreatic cancer, focusing on tumor-specific circadian dynamics and treatment optimization.
Description
This project aims to develop and optimize pre-clinical protocols using normal pancreas and patient-derived organoid cultures to inform treatment decisions in pancreatic ductal adenocarcinoma (PDA). The focus is on tumor-specific circadian clock dynamics and chronotherapeutic efficacy.