Award
National Eye Institute 5R01EY036009-02
Optic neuropathy in familial dysautonomia: determination of disease mechanisms and functional rescue.
Recipient
SCHEPENS EYE RESEARCH INSTITUTE
Award Amount
$795,539.00
Ceiling
$795,539.00
Awarded
April 07, 2026
Identifier
5R01EY036009-02
Award for research on optic neuropathy in familial dysautonomia to determine disease mechanisms and develop functional rescue treatments.
Description
This project aims to develop retina-specific treatments for familial dysautonomia (FD) by evaluating systemic and local therapeutic approaches, understanding the molecular mechanisms of RGC loss, and testing therapies in human iPSC-derived RGCs.