Award
National Cancer Institute 5U54CA261701-05
Project 3: The role of microenvironmental metabolites on metastatic progression
Recipient
Rockefeller University, New York, NY, United States
Award Amount
$298,581.00
Ceiling
$298,581.00
Awarded
September 08, 2025
Identifier
5U54CA261701-05
Research project investigating metabolic dependencies of breast cancer cells in metastatic progression, focusing on lung and liver colonization using advanced genetic and metabolomic techniques.
Description
This project aims to map metabolic dependencies of breast cancer cells during colonization of the lung and liver using CRISPR-based loss and gain of function approaches, and to investigate the role of niche cells through cell-specific metabolomics and single-cell sequencing.