Award
NIH Reporter #5R21OD037653-02
Rapid Development of Mouse Resource Strains through the Application of Prime Editors
Recipient
Jackson Laboratory, Bar Harbor, ME, United States
Award Amount
$221,250.00
Ceiling
$221,250.00
Awarded
August 13, 2025
Identifier
5R21OD037653-02
The award supports research to develop a novel genome editing approach using Prime Editors to create mouse resource strains rapidly and at reduced cost, potentially transforming genetic research and resource development.
Description
This project aims to develop and apply advanced genome editing techniques to accelerate the creation of mouse models for genetic research, with potential broad impacts on human health and disease understanding. It involves using Prime Editing technology to create genome-wide mouse resources more efficiently and cost-effectively.