Award

National Heart, Lung, and Blood Institute 11097301

Comparing Direct and Indirect Methods for Cascade Screening in Familial Hypercholesterolemia (FH) and Long QT Syndrome (LQTS)

Recipient

National Heart Lung and Blood Institute (NHLBI)

Award Amount

$696,129.00

Ceiling

$696,129.00

Awarded

July 31, 2025

Identifier

11097301

This NIH/NHLBI funded project conducts a randomized controlled trial to compare direct and indirect cascade screening methods for FH and LQTS, focusing on efficacy, ethics, and social impacts, with community engagement and health disparities considerations.

Description

A randomized controlled trial comparing direct versus indirect cascade screening methods for familial hypercholesterolemia and Long QT Syndrome. The study assesses efficacy, ethical principles, anxiety, perceived pressure, knowledge, reach, fidelity, and cost of the two contact approaches. The project emphasizes community engagement with the Amish community and addresses health disparities.

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