Award
National Institute of Allergy and Infectious Diseases 5R21AI188434-02
Modulation of neutrophil-endothelial interactions by ADAM10
Recipient
Washington University, Saint Louis, MO
Award Amount
$194,375.00
Ceiling
$194,375.00
Awarded
January 10, 2026
Identifier
5R21AI188434-02
NIH grant awarded to Washington University for research on how Staphylococcus aureus evades host immune defenses by modulating neutrophil-endothelial interactions, aiming to develop targeted therapies.
Description
This NIH grant supports research on host-pathogen interactions involving Staphylococcus aureus, focusing on neutrophil-endothelial cell interactions during infection to understand early disease pathogenesis and identify tissue-independent mechanisms to subvert host immune defenses, potentially leading to targeted therapies.