Award
National Cancer Institute 5R01CA295509-02
Endoplasmic Reticulum Stress in the function of cancer associated fibroblasts in pancreatic cancer
Recipient
Henry Ford Health + Michigan State University Health Sciences, East Lansing, MI
Award Amount
$450,102.00
Ceiling
$450,102.00
Awarded
December 31, 2025
Identifier
5R01CA295509-02
NIH/NCI awarded a research grant to study ER stress pathways in cancer associated fibroblasts in pancreatic cancer to identify therapeutic targets for improving treatment outcomes.
Description
This project aims to understand how endoplasmic reticulum (ER) stress promotes cancer associated fibroblasts (CAFs) pro-tumor functions in pancreatic cancer, with the goal of identifying new therapeutic targets to modulate the tumor microenvironment and improve treatment outcomes.