Award
NIH Reporter #5R01AI176457-04
Targeting purinergic signaling in Chagas disease
Recipient
NATIONAL RESEARCH COUNCIL OF ARGENTINA
Award Amount
$132,428.00
Ceiling
$132,428.00
Awarded
April 10, 2026
Identifier
5R01AI176457-04
Research project focused on investigating purinergic signaling pathways in Chagas disease to understand cardiac response and immune mechanisms, aiming to identify therapeutic targets.
Description
The project aims to determine the role of the purinergic system in the development of Chagas cardiomyopathy and how targeting these pathways impacts disease progression. It involves studying cardiac explants from transplanted patients and murine models to understand the cardiac response to infection and the immune mechanisms involved.