Award

National Heart, Lung, and Blood Institute 5R01HL162407-04

Targeting NOX4-dependent mitochondrial dysfunction, autophagy and defective calcium handling in AF

Recipient

National Heart Lung and Blood Institute (NHLBI)

Award Amount

$700,363.00

Ceiling

$700,363.00

Awarded

December 23, 2024

Identifier

5R01HL162407-04

NIH grant awarded to research mitochondrial dysfunction and calcium handling in atrial fibrillation, aiming to develop new therapeutics.

Description

Project involves research on atrial fibrillation focusing on NOX4, mitochondrial dysfunction, autophagy, and calcium handling. Uses innovative model organisms and genetic strains. Employs techniques such as patch clamp, confocal imaging, and optical mapping. Emphasizes development of therapeutics for AF and postoperative AF.

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