Award
National Institute of Neurological Disorders and Stroke 5R00NS119295-05
Structure and function of spontaneous network activity during circuit formation
Recipient
Duke University, Durham, NC, United States
Award Amount
$199,319.00
Ceiling
$199,319.00
Awarded
April 01, 2026
Identifier
5R00NS119295-05
Research to understand neural mechanisms of spontaneous network activity during circuit formation, focusing on neurons initiating SNA and genes linked to neurodevelopmental disorders, using Drosophila larval locomotor system as a model.
Description
This project aims to understand the neural mechanisms underlying spontaneous network activity (SNA) during circuit formation in neurodevelopment. Using the Drosophila larval locomotor system as a model, the study will identify neurons initiating SNA, analyze the development of activity patterns, and investigate genes involved, especially those linked to neurodevelopmental disorders.