# NIH Reporter #5F32DA062467-02

Neural mechanisms of psilocybin action in the frontal cortex

**Recipient:** Cornell University

**Award Amount:** $78,040.00
**Ceiling:** $78,040.00

**Awarded:** March 19, 2026

**Identifier:** 5F32DA062467-02

NIH funding supports research into how psilocybin affects frontal-cortex neural circuits, with the goal of understanding its potential therapeutic effects for substance use disorders.

### Description

This project examines psilocybin’s effects on neuronal activity and cellular and microcircuit mechanisms in the mouse medial frontal cortex, focusing on GABAergic interneurons and soma-dendrite coupling. The research aims to clarify how psilocybin shapes cortical information processing and may support improved addiction treatments.

[View original record](https://reporter.nih.gov/search/J7l2tQ4hHkqRePwGq3m5kA/project-details/11311806)