Award
National Institute of Allergy and Infectious Diseases (NIAID) 5R21AI190892-02
Regulation of the HA stem nanoparticle vaccine response by antigen duration
Recipient
Wake Forest University Health Sciences
Award Amount
$189,350.00
Ceiling
$189,350.00
Awarded
February 18, 2026
Identifier
5R21AI190892-02
The project investigates prolonged antigen delivery to enhance antibody response in infants to a nanoparticle vaccine targeting the HA stem, aiming to improve vaccine efficacy in infants under 6 months.
Description
This project aims to understand how antigen duration and vaccine construct modulate the infant B and T cell response to improve vaccine efficacy in infants under 6 months of age.