Award
National Cancer Institute 5R33CA281875-03
MASTER Scaffolds for Rapid, Single-Step Manufacture and Prototyping of CAR-T cells
Recipient
University of North Carolina at Chapel Hill, Department of Pharmacology
Award Amount
$401,164.00
Ceiling
$401,164.00
Awarded
July 24, 2025
Identifier
5R33CA281875-03
Development and validation of MASTER scaffolds to streamline CAR-T cell manufacturing, making it faster, cheaper, and more effective for cancer treatment.
Description
This project aims to develop and validate a novel technology called MASTER (Multifunctional Alginate Scaffolds for T cell Engineering and Release) that mediates every step of CAR T cell production, reducing processing time and costs while improving cell persistence and efficacy.