Award
NIH Reporter #5R35NS127216-04
Ion Channel Pharmacology for Pain and Epilepsy
Recipient
Harvard Medical School, Boston, MA
Award Amount
$1,087,133.00
Ceiling
$1,087,133.00
Awarded
February 26, 2026
Identifier
5R35NS127216-04
Research project funded by NINDS to develop selective ion channel modulators for treating pain and epilepsy by targeting specific neuronal ion channels.
Description
The project aims to understand the basic mechanisms controlling excitability of central neurons to develop therapeutics for pain and epilepsy by selectively targeting ion channels in neurons. It integrates research on ion channel regulation of firing patterns and pharmacological agents targeting voltage-dependent channels to design compounds that selectively inhibit or enhance specific neuron types.