Award
National Institute of General Medical Sciences 1R43GM156150-01
Molecular glue degraders for LRRK2
Recipient
LIFESENSORS, INC.
Award Amount
$299,978.00
Ceiling
$299,978.00
Awarded
August 13, 2024
Identifier
1R43GM156150-01
This NIH-funded project aims to develop molecular glue degraders for LRRK2 by utilizing a novel ubiquitination assay to facilitate drug discovery and clinical development in targeted protein degradation.
Description
Research project focused on developing molecular glue degraders targeting LRRK2 using a high-throughput ubiquitination assay to enable rational design and accelerate discovery and clinical development of protein degraders.