Award
National Institute of Allergy and Infectious Diseases 1R01AI187143-01A1
Th2 Memory in Chronic Type 2 Inflammation
Recipient
Brigham and Women's Hospital, Boston, MA, United States
Award Amount
$3,080,416.00
Ceiling
$3,080,416.00
Awarded
February 04, 2026
Identifier
1R01AI187143-01A1
NIH grant supporting research on immune mechanisms underlying allergic diseases focusing on Th2 progenitors using advanced molecular techniques and animal models to identify therapeutic targets.
Description
The project aims to understand and target the Th2 progenitor population involved in chronic type 2 inflammation, with potential implications for allergic diseases such as asthma and sinusitis. The research involves human tissue analysis and mouse models, utilizing cutting-edge single-cell gene expression, spatial transcriptomics, and flow cytometry.