Award
National Heart, Lung, and Blood Institute 5R01HL155295-04
Mechanisms of newborn pulmonary hypertension caused by chronic intrauterine hypoxia
Recipient
Loma Linda University, Department of Pediatrics
Award Amount
$763,188.00
Ceiling
$763,188.00
Awarded
November 21, 2024
Identifier
5R01HL155295-04
This NIH-funded research project aims to understand how chronic intrauterine hypoxia leads to newborn pulmonary hypertension by studying molecular pathways involving microRNA and mitochondrial dysfunction, with the goal of identifying therapeutic targets.
Description
Research project investigating the mechanisms of newborn pulmonary hypertension caused by chronic intrauterine hypoxia using a large animal model and gene manipulation techniques to study hypoxia-sensitive microRNA pathways.