Award
National Institute of Allergy and Infectious Diseases 5K08AI180429-02
The Role of ADAM9 in the Innate Immune Response to SARS-CoV-2 Infection
Recipient
University of Massachusetts Medical School Worcester
Award Amount
$190,058.00
Ceiling
$190,058.00
Awarded
December 08, 2025
Identifier
5K08AI180429-02
NIH grant awarded to University of Massachusetts Medical School to study ADAM9's role in the innate immune response to SARS-CoV-2, aiming to understand COVID-19 severity and lung injury mechanisms.
Description
This project investigates the role of ADAM9 in immune dysfunction caused by SARS-CoV-2, focusing on its impact on disease severity and acute lung injury (ALI). The study aims to elucidate the ADAM9/MDA5 innate immune pathway's role in COVID-19 pathogenesis and develop strategies for disease treatment and prevention.