Award
National Institute of Environmental Health Sciences 5R01ES032443-05
Mechanisms of Nanoparticle Modulation of Allergic Lung Disease
Recipient
North Carolina State University
Award Amount
$418,138.00
Ceiling
$418,138.00
Awarded
July 01, 2025
Identifier
5R01ES032443-05
This NIH-funded project studies the mechanism by which engineered nanoparticles worsen allergic lung disease, focusing on the interaction between nanoparticles and allergens that trigger harmful immune responses.
Description
Research project investigating how multi-walled carbon nanotubes (MWCNTs) exacerbate allergic airway disease by forming an allergen corona that activates PAR2 in lung macrophages, leading to pro-fibrotic signaling pathways.