Award

Massachusetts Executive Office of Veterans Services 2I01RD001372-06A2

Cell-type specific evaluation of globus pallidus pars externa as a translational target to improve sleep and arousal

Recipient

Ritchie Edward Brown

Awarded

April 14, 2026

Identifier

2I01RD001372-06A2

Research project awarded by Veterans Affairs to study cell-type specific modulation of the globus pallidus pars externa to improve sleep and arousal, aiming to develop treatments for sleep disorders and neurodegenerative diseases.

Description

The project focuses on evaluating cell-type specific modulation of the globus pallidus, pars externa (GPe), to improve sleep and arousal in Veterans. The research involves chemogenetic, optogenetic, and pharmacological approaches. The project aims to translate findings into potential treatments for sleep disorders and neurodegenerative conditions. The project is led by Ritchie Edward Brown, a Research Health Scientist at VA Boston Healthcare System.

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