# NIH Reporter #5F31HL182285-02

Defining the role of Fzd6 in lymphatic network development and function

**Recipient:** University of Minnesota

**Award Amount:** $35,951.00
**Ceiling:** $35,951.00

**Awarded:** August 06, 2026

**Identifier:** 5F31HL182285-02

The study will examine how FZD6 and planar cell polarity signaling affect lymphatic development and function, and assess whether FZD6 variants contribute to central conducting lymphatic anomaly.

### Description

The project investigates FZD6 as a potential cause of central conducting lymphatic anomaly by studying lymphatic network morphology, function, and cell behavior in loss-of-function mammalian models.

[View original record](https://reporter.nih.gov/search/47CiHD0bJ0u2LtDABS0zbg/project-details/11393576)