Award
National Institute of Neurological Disorders and Stroke 1R61NS138813-01A1
A novel gene therapy approach to reduce neurotoxicity in Parkinson's disease
Recipient
National Institute of Neurological Disorders and Stroke (NINDS)
Award Amount
$1,009,212.00
Ceiling
$1,009,212.00
Awarded
July 07, 2025
Identifier
1R61NS138813-01A1
NIH awarded a multiyear grant to develop a gene therapy to reduce neurotoxicity in Parkinson's disease using AAV-mediated ACMSD overexpression, including studies in rodent models.
Description
This project involves gene therapy research targeting Parkinson's disease, with a focus on reducing neurotoxicity through AAV-mediated overexpression of ACMSD. The project is funded by NIH/NINDS and is part of a multiyear award. The project includes pharmacodynamic, pharmacokinetic, and efficacy studies in rodent models.