Award
Texas A&M University Health Science Center 1F30AI194824-01A1
Coxiella burnetii effector CBU1198 inhibits JAK1 to downregulate interferon signaling during infection
Recipient
Texas A&M University Health Science Center
Award Amount
$38,708.00
Ceiling
$38,708.00
Awarded
May 11, 2026
Identifier
1F30AI194824-01A1
NIH awarded a research project to Texas A&M University Health Science Center to study how Coxiella burnetii effector CBU1198 inhibits JAK1 to downregulate interferon signaling during infection, aiming to understand host-pathogen interactions.
Description
The project focuses on studying the inhibition of JAK1 by the effector protein CBU1198 in Coxiella burnetii. The research aims to understand host-pathogen interactions and develop genetic tools. The project involves in vitro and in vivo models, including primary mouse and human cells.