Award
National Institute of General Medical Sciences 5R35GM141891-05
Mechanistic Pharmacodynamic Modeling for Drug Combination Responses
Recipient
Clemson University
Award Amount
$372,303.00
Ceiling
$372,303.00
Awarded
June 05, 2025
Identifier
5R35GM141891-05
The award supports research to develop advanced pharmacodynamic models for drug combination responses using mechanistic and computational approaches to enhance precision medicine.
Description
This project aims to improve simulation models for predicting patient responses to drugs and drug combinations by integrating innovative theory, computation, and experimental approaches. It focuses on proliferation and death of single cells, leveraging mechanistic models, network biology, and high-dimensional genetic screening.