Award
National Institute of Mental Health 5R01MH061876-23
Synaptotagmin C2B Domain as a Ca2+ Sensing Module
Recipient
University of Wisconsin-Madison
Award Amount
$368,770.00
Ceiling
$368,770.00
Awarded
March 24, 2026
Identifier
5R01MH061876-23
This NIH grant funds research on synaptotagmin isoforms to understand their role in calcium sensing and neurotransmitter release, with implications for neurological conditions such as addiction and schizophrenia.
Description
The project aims to elucidate the mechanisms of synaptotagmin isoforms that regulate neurotransmitter and hormone release, focusing on Ca2+ sensing and activity-dependent synaptic vesicle docking, to advance understanding of synaptic plasticity and related neurological conditions.