Award

NIH Reporter #5R01MH085974-15

Synaptic and dendritic physiology in the prefrontal cortex

Recipient

New York University, NY, United States

Award Amount

$506,300.00

Ceiling

$506,300.00

Awarded

December 06, 2023

Identifier

5R01MH085974-15

This award funds research on the interaction between thalamic inputs and interneurons in the mouse prefrontal cortex to understand cognitive functions and neuropsychiatric disorders using advanced neuroscience techniques.

Description

The project aims to determine how higher-order thalamus interacts with different populations of GABAergic interneurons to mediate inhibition in the mouse prefrontal cortex (PFC) using electrophysiology, optogenetics, and 2-photon microscopy. It studies thalamic inputs and their interaction with interneurons and pyramidal cells to understand cognitive function and mental health disorders.

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