Award
National Heart, Lung, and Blood Institute 5K08HL159289-04
Engineered microsystems to assess endothelial contribution to myeloproliferative neoplasm thrombosis
Recipient
University of Minnesota
Award Amount
$171,180.00
Ceiling
$171,180.00
Awarded
August 13, 2025
Identifier
5K08HL159289-04
This award funds a research project at the University of Minnesota to study the role of endothelial cells in thrombosis among patients with myeloproliferative neoplasms, aiming to understand molecular pathways that could lead to targeted therapies.
Description
Research project to define how endothelial cell activation contributes to myeloproliferative neoplasm thrombosis, focusing on the Gas6-Axl-MERTK signaling pathway and its role in pro-coagulant and pro-adhesive functions under shear stress conditions.