Award
NIH Reporter #5I01BX002378-10
Mechanisms driving airway inflammation in chronic lung disease
Recipient
Veterans Health Administration, Ann Arbor, MI, United States
Awarded
August 06, 2026
Identifier
5I01BX002378-10
Research project focused on understanding and intervening in the immune mechanisms driving COPD progression in Veterans, including studies on epithelial NF-κB, T lymphocytes, and dendritic cells.
Description
This project investigates mechanisms that account for persistent activation of the innate and adaptive immune systems in the lungs, leading to progressive emphysema and remodeling of small airways in Veterans with Chronic Obstructive Pulmonary Disease (COPD). The work aims to improve understanding of COPD and develop interventions to slow disease progression.