Award
National Institute of Neurological Disorders and Stroke 5R01NS134867-03
Molecular Mechanisms of Tubulin Polymerization Promoting Protein in Mitochondrial Function and Neuronal Survival
Recipient
University of Texas Health Science Center, San Antonio, TX
Award Amount
$397,839.00
Ceiling
$397,839.00
Awarded
July 06, 2026
Identifier
5R01NS134867-03
The award supports research to elucidate mitochondrial mechanisms of TPPP in promoting neuronal survival, with implications for Parkinson’s disease and related neurodegenerative disorders.
Description
This project aims to uncover the role of Tubulin Polymerization Promoting Protein (TPPP) in mitochondrial health and its implications in Parkinson’s disease and related neurodegenerative disorders. The research involves enzymatic assays, respirometry, LC-MS, biochemical, behavioral, pharmacological, cell biological, and genetic methodologies to understand the mechanisms of TPPP in neuronal survival.