Award
NIH Reporter #11424517
The Bit1 cell death pathway as a novel regulator of EGFR-TKI-induced apoptosis and resistance
Recipient
Xavier University of Louisiana
Award Amount
$150,000.00
Ceiling
$150,000.00
Awarded
August 20, 2026
Identifier
11424517
Research project funded by the National Cancer Institute to study the Bit1 cell death pathway's role in EGFR-TKI resistance in NSCLC, including mechanism elucidation and therapeutic target definition.
Description
The project investigates the role of the Bit1 cell death pathway in overcoming resistance to EGFR-TKIs in NSCLC. The project aims to elucidate mechanisms, define therapeutic targets, and evaluate in vivo efficacy. Engagement of undergraduate students in research.