Award
National Institute of General Medical Sciences 5R35GM156332-02
Decoding cell surface chemistry and function in Staphylococcus aureus
Recipient
Stanford University, Department of Chemistry, CA, United States
Award Amount
$385,000.00
Ceiling
$385,000.00
Awarded
July 28, 2026
Identifier
5R35GM156332-02
Award to Stanford University for research decoding cell surface chemistry in Staphylococcus aureus to understand biofilm formation and antibiotic sensitivity, aiming to develop new anti-infective strategies.
Description
This MIRA program deploys an unconventional and uniquely enabling cross-disciplinary experimental platform to decode the underlying cell-surface chemistry in Staphylococcus aureus that distinguishes friend from foe and underlies biofilm formation and sensitivity to antibiotics to ultimately drive the development of urgently needed new anti-infective strategies. This program will yield fundamental and translationally relevant discoveries and introduce broadly applicable strategies as many important cell-surface functions are achieved by polysaccharides, glycoconjugates, and heterogeneous, insoluble assemblies.