Award

NIH Reporter #1R21NS142731-01A1

Treatment of Neonatal Hypoxic Ischemic Injury with Echogenic Noble Gas Microbubbles

Recipient

New Jersey Institute of Technology, Newark, NJ, United States

Award Amount

$426,456.00

Ceiling

$426,456.00

Awarded

May 07, 2026

Identifier

1R21NS142731-01A1

The project focuses on using ultrasound-responsive microbubbles containing xenon and argon gases to treat neonatal hypoxic-ischemic encephalopathy, aiming to reduce brain injury and improve neurological outcomes.

Description

This NIH-funded project aims to develop a novel, non-invasive treatment for neonatal hypoxic-ischemic encephalopathy using microbubbles loaded with xenon and argon gases, activated by ultrasound to deliver targeted therapy across the blood-brain barrier, with the goal of reducing brain injury and preserving neurological function in affected infants.

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