Award
National Institute of Diabetes and Digestive and Kidney Diseases 5R00DK132460-04
Defining the role of Sf1 in urethral closure
Recipient
University of Missouri-Columbia
Award Amount
$245,414.00
Ceiling
$245,414.00
Awarded
June 27, 2025
Identifier
5R00DK132460-04
Research project funded by NIH to study the role of Sf1 in urethral closure and mechanisms of hypospadias, led by University of Missouri-Columbia.
Description
The project focuses on the role of Steroidogenic Factor 1 (Sf1) in urethral closure. The research aims to understand mechanisms involved in hypospadias. The project involves studying androgen signaling and SF1+ cells in penis development, including genetic models such as cell ablation and knockout mice. The project aims to contribute to prevention strategies for hypospadias.