Award
National Institute on Deafness and Other Communication Disorders 5R01DC012379-14
Functional organization of the superior temporal gyrus for speech perception
Recipient
University of California, San Francisco
Award Amount
$681,817.00
Ceiling
$681,817.00
Awarded
June 25, 2025
Identifier
5R01DC012379-14
Research project funded by NIDCD to study how speech is processed in the brain using neurophysiological recordings during neurosurgery, aiming to improve diagnosis and treatment of language disorders.
Description
The aim of this research is to reveal the fundamental mechanisms that underlie comprehension of spoken language. An understanding of how speech is coded in the brain has significant implications for the development of new diagnostic and rehabilitative strategies for language disorders (e.g., aphasia, dyslexia, autism). Abnormal perception of phonemes is a central component to language disability in these conditions. The project will examine the cortical representation of speech sounds using neurophysiological recordings obtained during neurosurgical procedures. High-density electrode arrays and advanced signal processing will be used to understand how the brain extracts linguistic elements from complex acoustic speech signals, aiming to improve understanding and treatment of language disorders.