Award
National Institute of Allergy and Infectious Diseases (NIAID) 5R01AI145687-07
Structural definition of CD4-induced HIV-1 Env conformational changes required for infection
Recipient
Duke University, Durham, NC, United States
Award Amount
$791,914.00
Ceiling
$791,914.00
Awarded
July 27, 2026
Identifier
5R01AI145687-07
Research grant awarded to study HIV-1 Env conformational changes to inform vaccine and therapeutic development.
Description
This grant investigates the stepwise conformational changes of the HIV-1 envelope (Env) protein during receptor mediated entry into host cells, focusing on early to later stages of Env opening and its implications for vaccine and drug design.