Award
Washington University in St. Louis 11304903
Optimizing Minoxidil Delivery for Persistent Elastin Deposition in the Murine Vaginal Wall
Recipient
Washington University
Award Amount
$441,884.00
Ceiling
$441,884.00
Awarded
May 28, 2026
Identifier
11304903
NIH awarded a grant to Washington University for research on optimizing minoxidil delivery to enhance elastin deposition in the vaginal wall, aiming to treat pelvic organ prolapse with a $441,884 multiyear award.
Description
This NIH grant aims to optimize the delivery of minoxidil to promote vaginal elastogenesis to treat pelvic organ prolapse. The project involves biochemical and biomechanical assays, exploring different delivery methods, dosages, and durations to enhance elastic fiber deposition and stability in the vaginal wall. The award amount is approximately $441,884, with a focus on non-invasive biologic therapies to improve women's health outcomes.