Award
National Institute of Allergy and Infectious Diseases 5R37AI034495-34
In Vivo Prevention of Murine GVHD
Recipient
University of Minnesota, Minneapolis, MN
Award Amount
$589,718.00
Ceiling
$589,718.00
Awarded
June 16, 2026
Identifier
5R37AI034495-34
This NIH grant supports research to prevent and treat GVHD by studying immune regulatory cells and mechanisms, focusing on translational applications in transplantation and autoimmunity.
Description
Research grant focusing on immune regulation and transplantation to prevent and treat graft-vs-host disease (GVHD) via innate lymphoid type 2 cell (ILC2) anti-inflammatory and tissue reparative properties. The project aims to develop novel approaches and gain biological insights into immune system control by IL33, ILC2s, and regulatory T cells (Tregs) with translational applications for hematopoietic stem cell and solid organ transplantation and autoimmunity settings.