Award
NIH Reporter #1F31DK145094-01A1
Elucidating the real-time search dynamics of a transcription factor at its sole target
Recipient
University of Pennsylvania
Award Amount
$49,538.00
Ceiling
$49,538.00
Awarded
February 13, 2026
Identifier
1F31DK145094-01A1
The award supports research to understand how a transcription factor locates and binds its specific target in the genome using advanced imaging and genomic techniques, providing insights into gene regulation and chromatin biology.
Description
This project aims to elucidate the mechanisms of transcription factor search and binding dynamics at a native genomic locus using live-cell single-molecule tracking, with implications for understanding gene regulation and chromatin biology.