National Institute of Neurological Disorders and Stroke 1R21NS130385-01A1

Epilepsy after penetrating brain injury

This award funds research on epilepsy development following penetrating brain injuries using a rat model, focusing on the impact of toxic metal fragments like copper and lead to improve clinical care and outcomes.

Description

Brain trauma is a common cause of epilepsy, especially trauma from penetrating injuries (e.g., gunshot wounds). This project uses a rat model of penetrating brain injury to study factors contributing to epilepsy and long-term neurological outcomes. The study focuses on the role of toxic metal fragments (copper and lead) in the development of epilepsy, examining how exposure duration influences damage and seizure risk. The research aims to guide clinical care to reduce epilepsy risk and improve outcomes.

View original record