# NIH Reporter #1F31AG101818-01

The Effect of Antidepressants on Cognitive Performance and Alzheimers Disease and Related Dementias Blood-Based Biomarkers

**Recipient:** Wake Forest University Health Sciences

**Award Amount:** $50,114.00
**Ceiling:** $50,114.00

**Awarded:** August 14, 2026

**Identifier:** 1F31AG101818-01

The project will use ASPREE cohort data to study how antidepressant treatment relates to cognitive performance and Alzheimer's disease blood-based biomarkers in older adults, while training the applicant in biostatistics, causal inference, and aging research.

### Description

NIH-funded research project estimating the effects of antidepressant treatment, overall and by drug class, on changes in cognitive performance and blood-based biomarkers of Alzheimer's disease pathology.

[View original record](https://reporter.nih.gov/search/J7l2tQ4hHkqRePwGq3m5kA/project-details/11385072)